Medically reviewed by Alan Carter, Pharm.D. — composed by Jill Seladi-Schulman, Ph.D. Top top December 19, 2018

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Acetaminophen (Tylenol) and also ibuprofen (Advil) room both over-the-counter (OTC) medications that deserve to be supplied to relieve pain.

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These medications are two different species of pain relievers. Acetaminophen, sometimes provided as APAP, is its very own type, while ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID).

Generally, it’s for sure to take it acetaminophen and also ibuprofen together, however you’ll desire to salary close fist to exactly how much you take of every medication.

The crucial to safely acquisition acetaminophen and ibuprofen is knowing how much you’re acquisition at a time and how often.

Acetaminophen dosage

The maximum for sure dosage of acetaminophen for anyone over the period of 12 is 4,000 milligrams (mg) every day. However even this quantity can harm some people’s livers, therefore aim for no more than 3,000 mg per day.

For youngsters under the age of 12, it’s best to inspect with their health care provider to determine the safest sheep for their body weight.

Keep in mental that countless OTC medications contain acetaminophen in a variety of doses, usually 325 mg, 500 mg, or 650 mg.

Some instances of brand-name OTC medications that might contain acetaminophen include:


Remember: as soon as looking in ~ labels, girlfriend might also see acetaminophen listed as APAP.

Ibuprofen dosage

Avoid taking an ext that 1,200 mg of ibufrofen in a solitary day. OTC ib frames is often discovered in 200 mg pills. This equates to 6 pills a day. Still, girlfriend should constantly verify exactly how much is in each pill.

Again, because that children, it’s best to questioning their medical care provider about the safest sheep for your weight.

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If you have prescription-strength ibuprofen, speak to your prescriber prior to mixing it with any other medications, including acetaminophen.


The recommended limits for adults and children end 12 are:

3,000 mg every day of acetaminophen1,200 mg per day the ibuprofen

For youngsters under the period of 12, contact their medical care provider or refer to the product brand for dosage guidelines.

You deserve to take ibuprofen and also acetaminophen in ~ the very same time. Just make sure to no take an ext than the recommended dose.

Some world experience part stomach or abdominal muscle pain when taking the two drugs together. In this case, it’s far better to alternate when you take it each medication.

For example, you could take ibuprofen first, adhered to by acetaminophen 4 hours later, and also then repeat this procedure as needed.

You could also alternate days. For example, if you take it ibuprofen ~ above Monday, take paracetamol on Tuesday and so on.