A homologous chromosome comes to one of a pair of chromosomes v the very same gene sequence, loci, chromosomal length, and also centromere location. A homologous pair consists of one paternal and one maternal chromosome. In humans, there room a full of 46 chromosomes in the cell core of a somatic cell. Half of them (22 autosomes + X or Y chromosome) space inherited indigenous the father and also the other half (22 autosomes + X chromosome), from the mother. Every maternal chromosome has actually a equivalent paternal chromosome; castle pair up during meiosis. Typically, a woman will have 23 homologous chromosomes conversely, a masculine will have 22. That is since the sex chromosomes, X and also Y, in males space not homologous. The pairing up of homologous chromosomes throughout meiosis is essential to promote genetic variation. Due to the fact that of the hereditary recombination that occurs between homologous pairs at meiosis, the resulting haploid gametes save on computer chromosomes that space genetically different from each other. This amplifies gene pool, thereby, raising the possibilities of gaining genes essential to organic fitness and survival.

You are watching: How would you know if two chromosomes were homologous

Want to know about homologous chromosome? sign up with us and also participate in our Forum discussion: Difference between Homologous Chromosomes and also Sister Chromatids

Homologous chromosome definition

In biology, homologous chromosomes room paired chromosomes. They basically have the exact same gene sequence, loci (gene position), centromere location, and chromosomal length. Although they may have actually the same hereditary sequence and loci, they might differ in alleles. The homologous pair is made up of a paternal chromosome and a maternal chromosome. These chromosomes pair up during meiosis but not throughout mitosis.


The ax homologous came from Greek homologos, an interpretation “agreeing” or “of one mind”. It is a mix of homos, an interpretation “same” and also logos, an interpretation “relation”. The ax chromosome was coined in 1889 by German anatomist, Wilhelm von Waldeyer-Hartz. The was acquired from the Greek khrōma, meaning “color” because it readily stained with straightforward dyes. Synonym: homologue.

Homologous chromosomes vs. Heterologous chromosomes

When chromosomes space homologous, it way that they room the same, at the very least in terms of the gene sequences and also loci. Heterologous, in essence, means “different”. This way that heterologous (non-homologous) chromosomes would, therefore, pertain to any kind of two chromosomes that space different, such together in terms of gene sequence and also loci. Throughout meiosis, homologous chromosomes might naturally exchange hereditary material. Heterologous chromosomes execute not. However, there room instances wherein heterologous chromosomes perform exchange chromosomal parts. When this occurs, the process is dubbed chromosomal translocation. The is a kind of mutation that could lead to major chromosomal aberrations. For the comparison between homologous chromosomes and also heterologous chromosomes, watch table below.

Homologous chromosomes have alleles ~ above the very same genes located in the very same loci. Heterologous chromosomes have actually alleles on various genes.
Pairs up during meiosis Does no pair up during meiosis
Gene exchanges may occur at synapse. Gene exchanges may occur at translocation.
Basic parts:

centromere (kinetochore) lengthy arms (q) brief arms (p)
Basic parts:

centromere (kinetochore) long arms (q) quick arms (p)

22 autosomal chromosomes XX sex chromosomes

XY sex chromosome any type of chromosome the supposedly belongs to a chromosomal pair

Homologous chromosome vs. Sister chromatids

At meiosis, each of the homologous chromosomes is made up of two similar chromatids joined with each other by a typical kinetochore (centromere). The the same chromatids are specifically called sister chromatids to identify them native the so-called non-sister chromatids. Before cell divisions, the chromosomes in the nucleus appear as threadlike strands (called chromatins). Once a cabinet is fated to undergo mitosis or meiosis, castle condense right into thicker structures. By this time, the dyed is referred to as a chromosome. The DNA in the chromosome replicates by DNA replication during the S phase of the interphase. After ~ replicating, there would have actually been two DNA copies, each current in a strand referred to as chromatid. The 2 chromatids join by a usual centromere are referred to as sister chromatids. The chromatids of the other member of a homologous pair are described as non-sister chromatids.


Homologous chromosomes mirroring sister and non-sister chromatids. Hereditary recombination deserve to occur in between non-sister chromatids.

Explore more! sign up with our Forum: Difference between Homologous Chromosomes and also Sister Chromatids. Let’s talk!


The chromosomes of a eukaryotic bio cell are located in the nucleus. The chromosomes in the nucleus are of 2 sets. One set would come from the masculine gamete (sperm cell) and also the other set, indigenous the mrs gamete (egg cell). Before fertilization, both gametes space haploid. Once the sperm cell efficiently fertilizes the egg cabinet the resulting zygote is a diploid, which method the union the the 2 haploid cells results in a solitary cell v two sets of chromosomes: one set that is maternally-derived and also another set that is paternally-derived. Every maternal chromosome has a corresponding paternal chromosome that the very same gene sequence, gene loci, chromosomal length, and also centromere location. The pair come close to each other throughout meiosis so that they could exchange genes in between sister and also non-sister chromatids. Although both members the the homologous pair have similar genes and also loci, they might differ in the alleles. For example, both of them bring genes coding for the eye color trait. One has actually alleles for the brown-eye trait whereas the other, for the blue-eye trait. In this case, the alleles are different and also the homologous chromosomes are defined as heterozygous. On the contrary, once the alleles space the very same (e.g. Both alleles for the exact same gene code for the blue-eye trait) then, lock are stated to it is in homozygous. The significance of alleles was demonstrated by Gregor Mendel v his pioneering functions in genes using garden peas. He was able to present that one of the alleles might be leading over the other. In this case, only one allele will be expressed. A properties demonstrating this pattern is described as Mendelian inheritance. Nevertheless, in humans, genetic expressions room not straightforward. Countless of the human being traits do not conform to the Mendelian pattern of inheritance. In this regard, lock are referred to as non-Mendelian.

Homologous chromosomes Maternal chromosome head chromosome Inherited native the mother Inherited indigenous the dad Same hereditary sequence, loci, chromosomal length, and also centromere place Alleles may be the very same or various

Pairing process

Meiosis is a type of cell division wherein diploid organisms halve their variety of chromosomes and homologous chromosomes pair up. In contrast, mitosis (another type of cell division) outcomes in two daughter cells, every containing the same chromosomal number as the parent cell. In meiosis, a diploid (2n) cell will provide rise to 4 haploid (n) cells. The cells that undergo meiosis are the gametes producing haploid sperm cell and also egg cell. Haploidy is crucial so that at fertilization the chromosomal number continues to be the same throughout generations. In order to accomplish haploidy, the cell undergoes two consecutive atom divisions. Lock are referred to as meiosis I and meiosis II. To prepare the cell to meiosis, among the significant preparatory procedures is DNA replication. The chromosomes duplicate their DNA, an especially in the S phase of interphase. In ~ this point, every of the chromosomes will consist of two strands (sister chromatids) joined at the centromere. The pairing (synapse) of homologous chromosomes will occur at prophase I. DNA exchanges occur in between homologous chromosomes via homologous recombination and crossover at chiasmata between non-sister chromatids. Then, the homologous pairs heat up at the metaphase plate. Next, the homologous chromosomes separate throughout anaphase I and move to the opposite poles of the cell. Then, the cell divides for the an initial time throughout telophase I bring about two gene non-identical daughter cells however with sisters chromatids quiet intact. Every cell will certainly undergo meiosis II so the the resulting daughter cells will certainly each have actually a chromosomal number reduced by half.

Human karyotype


The homologous chromosomes that humans based on the gene sequences, loci, and centromere location. A somatic cell (2n) consists of 46 chromosomes and also 22 of them space homologous. If the sex chromosomes are both X chromosomes, climate the total variety of homologous chromosomes is 23.

In humans, the nucleus frequently contains 46 chromosomes. Thus, there space 22 bag of autosomes with about the very same length, staining pattern, and also genes with the exact same loci. As for the sex chromosomes, the 2 X chromosomes are considered as homologous whereas the X and Y chromosomes are not. Thus, females have 23 homologous chromosomes (i.e. 22 autosomes + 1 X-X chromosomes) vice versa, males have only 22.


The chromosomes are important to all living things due to the fact that they bring the genetic instructions for every one of the cell’s activities. They additionally bear the genetic information that determines the characteristics of an organism. Homologous chromosomes, therefore, are an important in the same way. They bring genetic details that has been passed down from one generation to the next. And also since alleles may possibly be various in the very same gene, the an outcome is varying phenotypes. Thus, the distinctiveness of an separation, personal, instance of the same species is established. Except this, the biology is capable of reproducing offspring the is genetically different from itself and from the rest of that descendants. The homologous chromosomes in the cell nucleus of the organism’s gamete pair up throughout meiosis. This occasion is an important to promote genetic variation. The homologous pair exchanges genes via hereditary recombination for this reason that hereditary diversity might be promoted. This is concerned as one of the advantages of having actually been able come reproduce sexually. Those that reproduce asexually develop a clone that themselves. Thus, this could reduce the gene pool. A little gene pool way low hereditary diversity. It could be unfavorable due to the fact that it method there is much less opportunity in acquiring genes crucial for adapting to an atmosphere prone come inexorable physicochemical changes. In contrast, greater hereditary variability means a greater propensity to acquire better genes. High hereditary diversity also method a large gene pool. This, in turn, implicates boosted chances of acquiring genes that might enhance biological fitness and also survival.

Got questions on homologous chromosomes? join our Forum: Difference in between Homologous Chromosomes and Sister Chromatids. Our neighborhood may have the ability to help!

See also



Chromosome Mutations

Mutations can also influence the phenotype of one organism. This indict looks in ~ the results of chromosomal mutations, such as nondisjunction, deletion, and duplication. ..

Read More


Meiosis and also Alternation that Generations

Plants are characterized by having alternation that generations in your life cycles. This accuse is a testimonial of plant mitosis, meiosis, and also alternation the generations. ..

Read More


Chromosomes X and Y and also Sex decision

This indict looks in ~ sex decision via the sex chromosomes, X and also Y. Check out it to get much more info on X and Y chromosomes and the hereditary traits inherited via this two...

Read More

live independence Assortment and Crossing over

This tutorial explains the live independence assortment that chromosomes and crossing end as necessary events in meiosis. Review this tutorial to know more details in every of this meiotic events and how castle promote genetic diversity in sexually-reproducing organisms...

Read More


Humans are diploid creatures. This way that for every chromosome in the body, over there is another one to enhance it. However, there room organisms the have more than two sets the chromosomes. The condition is called polyploidy. Know an ext about this topic v this tutorial...

Read More

hereditary Information and Protein synthesis

Genes are expressed through the process of protein synthesis. This fancy tutorial offers an comprehensive review of the various steps that the biological production of protein beginning from the gene up to the process of secretion. Also included space topics ~ above DNA replication throughout interphase the the cell cycle, DNA mutation and also repair mechanisms, gene pool, modification, and diseases...

See more: 49: How To Say I Miss You In Italian ? How To Say I Miss You! In Italian

Read More

The contents on this website is for information only. It is not intended to administer medical, legal, or any kind of other skilled advice. Any information right here should no be taken into consideration absolutely correct, complete, and also up-to-date. See expressed below do not necessarily reflect those of biologic Online, the staff, or its partners. Prior to using our website, please review our Privacy Policy.