The ax ‘cuboidal’ might seem confusing if you were to look in ~ the apical surface of cuboidal epithelial cells and also only check out hexagonal shapes. Regardless of this external appearance, a cut that is perpendicular to the surface ar of the cells would display that the cells room equally wide as they space tall, creating a square profile through a spherical nucleus at its facility (Figure 1).Simple cuboidal cells room classified as an easy since they consist of only a solitary layer of cells. Depending upon their location, some basic cuboidal cells, such as the people lining the surface of the lines the lumina that convoluted tubules in the kidney, may have actually microvilli on their surface ar (not presented in figure). To learn an ext about the general classification and also structure the epithelial cells, see the framework of Epithelial organization on our residence page.

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Figure 1. Diagram of simple cuboidal epithelium.


By lining the surface ar of miscellaneous ducts of various glands and also organs, basic cuboidal cells are able to administer a layer of protection from abrasion, foreign particles, invading bacteria and also excessive water loss (due to its selective permeability) to the basic tissue.In the kidney tubules, the cells help in the absorption and transport of filtered substances. In the kidney tubules, the cells help in the absorption and transportation that filtered substances. Come learn more about these functions and also other general functions of epithelial cells, check out the functions section on our house page.


Simple cuboidal epithelium currently the surface of little excretory ducts in assorted organs and glands in the body, compose some of the kidney tubules in the kortex of the kidney, and create the extending of the ovary.Several instances of their locations are disputed below.

Kidney Tubules

In the kidney, basic cuboidal epithelium lines the lumina of convoluted tubules. The polarity that the cells allows the basal lateral surface (which is in contact with the basal lamina and the underlying tissues) and the apical surface ar (which lines the lumen whereby the particles are) come have different surface proteins. These unique surfaces enable the straightforward cuboidal cell to facilitate in the absorption and also transportation of substances that room filtered by the kidney (Figure 2).In the proximal convoluted tubules, the apical surface ar of the epithelium is lined with microvilli, developing a brush border, giving it a fuzzy appearance.The microvilli can assist in help to transport product by “brushing” the molecules in the lumen of the tubules.

image from: Figure 2. A slide of the the kidney medulla showing an easy cuboidal epithelium lining the lumina (indicated by the lu) of part convoluted tubules. The locations are pointing at the sheet of the tubule, whereby the darker heat of pink is the basement membrane.

image from: Figure 3. Germinal epithelium comprised of an easy cuboidal cells that covers the ovary.

Covering the the Ovaries

On the ovarian surface, an easy cuboidal cells consist of the ovarian surface epithelium and are modified peritoneum that is acquired from the mesothelium that spanned the emerging ovaries (Figure 3). Basic cuboidal epithelial cells’ ability to rapidly divide and also proliferate allows them to fix ovulatory defects that take place on the ovarian surface, especially throughout the time that ovulation.There have additionally been studies linking the majority of ovarian cancer reasons to the basic cuboidal layer.

Respiratory Bronchiole

Simple cuboidal epithelium currently the wall surface of the respiratory tract bronchiole (Figure 4) and also may have actually cilia in the proximal section of the bronchiole. The single layer of an easy cuboidal epithelium permits the respiratory bronchioles to create a transitional zone where air conduction and exchange that gases or respiration can take place.
image from: Figure 4.Simple cubodial epithelium present the wall surface of the smaller sized respiratory bronchiole.

Eroschenkodi, V. P. (2005). diFiore"s Atlas that Histology with useful Correlations (10th ed.). Philadelphia, PA: Lippincott Williams and also Wilkins.

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Gartner, L.P. & Hiatt, J.L. (2007). Color Textbook the Histology (3rd ed.). Philadelphia, PA: Saunders Elsevier.